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the science

the science  

Marion Mcnabb, Dr PH, MPH

President of Cannabis Center of Excellence

The Undoo® Veterans Study is being conducted in tandem with the CCOE Veterans Cannabis Access Program (VCAP).

The Cannabis Center of Excellence, INC. (CCOE, INC.) is a registered Massachusetts 501c3 non-profit organization that conducts citizen-science-focused population studies and programs in the areas of community engagement, medical cannabis, adult-use cannabis, and social justice in the cannabis industry. The CCOE serves as a virtual resource & network of cannabis industry professionals, academics, policy makers, healthcare providers, consumers, and patients who aim to break the stigma and advance social justice in the cannabis industry.

key highlights from preliminary undoo® veterans study report:

  • Overall, more participants (about a 50% increase) felt calm, cool, comfortable, and like the effects they were experiencing after taking the products.

  • Confident, competent, and energetic became the most reported feelings after taking the product.

  • Among other feelings participants reported having, mental clarity (40%), increased energy (40%). The range of psychologically bad feelings also decreased dramatically after taking the products, and more participants felt lively.

  • In general, participants reported that using undoo® products significantly enhances their physical and mental health conditions. Most participants will likely use the products again or suggest the products to someone else.

Preliminary Research Results: McNabb, et al May 2023. undoo® Research Study led by the Cannabis Center of Excellence.

The Undoo® Veterans Study is being conducted in tandem with the CCOE Veterans Cannabis Access Program (VCAP).

(CCOE, INC.) is a registered Massachusetts 501c3 non-profit organization that conducts citizen-science-focused population studies and programs in the areas of community engagement, medical cannabis, adult-use cannabis, and social justice in the cannabis industry. The CCOE serves as a virtual resource & network of cannabis industry professionals, academics, policy makers, healthcare providers, consumers, and patients who aim to break the stigma and advance social justice in the cannabis industry.

key highlights from preliminary undoo® veterans study report:

  • Overall, more participants (about a 50% increase) felt calm, cool, comfortable, and like the effects they were experiencing after taking the products.

  • Confident, competent, and energetic became the most reported feelings after taking the product.

  • Among other feelings participants reported having, mental clarity (40%), increased energy (40%). The range of psychologically bad feelings also decreased dramatically after taking the products, and more participants felt lively.

  • In general, participants reported that using undoo® products significantly enhances their physical and mental health conditions. Most participants will likely use the products again or suggest the products to someone else.

Preliminary Research Results: McNabb, et al May 2023. undoo® Research Study led by the Cannabis Center of Excellence.

How do undoo® products work?

All humans (including all mammals) have a system of receptors in our brains and bodies that activate/respond to chemical compounds found in the cannabis plant (cannabinoids). This system is called the endocannabinoid system and its function is to maintain a state of homeostasis within our bodies.

Endocannabinoid System (ECS) & THC

Homeostasis is our body maintaining an internal stable environment despite its external environment (think of our body maintaining a temperature of 98.6 degrees). The endocannabinoid system plays a role in the body’s most basic functions from sleeping and eating to relaxing and memory recollection.

You can think of your body’s receptors (CB1 and CB2 receptors) as “locks'' while you can think of cannabinoids as “keys”. Our bodies naturally produce cannabinoids called “endogenous cannabinoids (aka endocannabinoids)” and there are plant cannabinoids such as CBD and THC called “phytocannabinoids”. These cannabinoid “keys” bind with the receptor “locks” and affect various bodily functions.

The THC “key” binds with the CB1 receptor “lock”.

This “lock and key” concept is the basis of Undoo’s patented formulas (see patent: here)

How do undoo® products work?

All humans (including all mammals) have a system of receptors in our brains and bodies that activate/respond to chemical compounds found in the cannabis plant (cannabinoids). This system is called the endocannabinoid system and its function is to maintain a state of homeostasis within our bodies. Homeostasis is our body maintaining an internal stable environment despite its external environment (think of our body maintaining a temperature of 98.6 degrees). The endocannabinoid system plays a role in the body’s most basic functions from sleeping and eating to relaxing and memory recollection.

Endocannabinoid System (ECS) & THC

You can think of your body’s receptors (CB1 and CB2 receptors) as “locks'' while you can think of cannabinoids as “keys”. Our bodies naturally produce cannabinoids called “endogenous cannabinoids (aka endocannabinoids)” and there are plant cannabinoids such as CBD and THC called “phytocannabinoids”. These cannabinoid “keys” bind with the receptor “locks” and affect various bodily functions.

The THC “key” binds with the CB1 receptor “lock”.

This “lock and key” concept is the basis of Undoo’s patented formulas (see patent: here)

What is olivetol?

Olivetol is a polyphenol compound that can be found in lichens, many plants, made synthetically and is also an important intermediate in the synthesis of cannabinoids.

  • Taslimi, P.; Gulçin, İ. Antioxidant and anticholinergic properties of olivetol. J. Food Biochem.2018, 42, e12516.
  • Koksal, Z.; Kalin, R.; Kalin, P.; Karaman, M.; Gulcin, İ.; Ozdemir, H. Lactoperoxidase inhibition of some natural phenolic compounds: Kinetics and molecular docking studies. J. Food Biochem.2020, 44, e13132.
  • Raharjo, T.J.; Chang, W.-T.; Choi, Y.H.; Peltenburg-Looman, A.M.G.; Verpoorte, R. Olivetol as product of a polyketide synthase in Cannabis sativa L. Plant Sci.2004, 166, 381–385.
  • Hladyszowski, J.; Zubik, L.; Kozubek, A. Quantum Mechanical and Experimental Oxidation Studies of Pentadecylresorcinol, Olivetol, Orcinol and Resorcinol. Free Radic. Res.1998, 28, 359–368.

THC molecule

olivetol molecule

What is olivetol?

Olivetol is a polyphenol compound that can be found in lichens, many plants, made synthetically and is also an important intermediate in the synthesis of cannabinoids.

  • Taslimi, P.; Gulçin, İ. Antioxidant and anticholinergic properties of olivetol. J. Food Biochem.2018, 42, e12516.
  • Koksal, Z.; Kalin, R.; Kalin, P.; Karaman, M.; Gulcin, İ.; Ozdemir, H. Lactoperoxidase inhibition of some natural phenolic compounds: Kinetics and molecular docking studies. J. Food Biochem.2020, 44, e13132.
  • Raharjo, T.J.; Chang, W.-T.; Choi, Y.H.; Peltenburg-Looman, A.M.G.; Verpoorte, R. Olivetol as product of a polyketide synthase in Cannabis sativa L. Plant Sci.2004, 166, 381–385.
  • Hladyszowski, J.; Zubik, L.; Kozubek, A. Quantum Mechanical and Experimental Oxidation Studies of Pentadecylresorcinol, Olivetol, Orcinol and Resorcinol. Free Radic. Res.1998, 28, 359–368.

THC molecule

olivetol molecule

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